DOE/LANL Jurisdiction Fire Danger Rating:
  1. LANL Home
  2. Media
  3. Newsletters
  4. STE Highlights
November 18, 2025

Can AI help fast track advanced fuels for nuclear reactors?

Novel technique cuts testing time, boosts confidence in predictions

Pellet Fuel Feature
Nuclear fuel pellets Credit to: Los Alamos National Laboratory

Los Alamos researchers and collaborators have demonstrated an uncertainty quantification framework for predicting how nuclear fuel deforms under reactor conditions. They focused on uranium dioxide creep, a mechanism that governs the stress state of the fuel and influences how the fuel pellet responds under both normal operating conditions and accident scenarios.
 
Read the paper  
 
Why this matters: In line with the nation’s energy goals, this approach could help accelerate the qualification of fuels for nuclear reactors — a typically slow, expensive process requiring years of in-reactor experiments. It opens new opportunities to strengthen safety and increase reactor efficiency.

 

This figure shows how lower-length-scale (LLS) parameters inform a surrogate model and refine values for a uranium dioxide creep problem using Bayesian inference.
This figure shows how lower-length-scale (LLS) parameters inform a surrogate model and refine values for a uranium dioxide creep problem using Bayesian inference. Credit: Conor Galvin, Los Alamos National Laboratory


What they did: By combining advanced computer modeling and data analysis with machine learning, the team developed this new framework. The researchers:

  • Combined physics-based mechanistic models and experimental data within a Bayesian inference approach to make accurate predictions accounting for uncertainty.
  • Used machine learning to efficiently run those models millions of times, thus quickly performing simulations and refining physics-based parameters related to the material’s microscopic properties that control how it behaves.
  • Used mechanistic material models developed by Los Alamos to prove historical scatter in experiments is due to extremely small stoichiometry changes.
  • Compared real-world experimental data with a mechanistic model using a statistical method, Bayesian inference, to make their predictions more accurate.

Funding: The work at Los Alamos was supported by the U.S. Department of Energy’s Nuclear Energy Advanced Modeling and Simulation (NEAMS) program, and by an award from the U.S. Department of Energy’s Office of Nuclear Energy and Westinghouse Electric Company.

LA-UR-25-31133

Share

Stay up to date
Subscribe to Stay Informed of Recent Science, Technology and Engineering Highlights from LANL
Subscribe Now

More STE Highlights Stories

STE Highlights Home
D Wave Chip

Physicists use D-Wave chip to study quantum effects

How quantum tunneling helps magnets choose a state

Cunningham

Cunningham named to ASME’s 2026 Mechanical Engineering Watch List

Los Alamos grad student uses research, humor and outreach to make nuclear science approachable

Bouabid Ryan

Bouabid earns Springer Thesis Prize for neutrino studies

Award recognizes research conducted in part at Los Alamos

AI Acoustics

It’s boiling over! Acoustic AI hears what cameras can’t see

A new method uses sound to predict unsafe conditions

Neptunium Oxide

First-ever measurements unlock hidden properties of neptunium oxide

New insights could improve prediction and management of long-lived radioactive materials

Metal Failure

No longer a shot in the dark: Predicting metal failure under stress

The design and safety of defense systems could benefit from this model

Los Alamos National Laboratory

P.O. Box 1663

Los Alamos, NM 87545

(505) 667-5061

At The Lab

  • Business Opportunities
  • Jobs
  • Organizations
  • Research Library
  • User Facilities

Information

  • Emergency
  • Ombuds
  • Reading Room
  • Resources
  • Science Museum

For Employees

  • AskIT
  • LANLInside
  • MyMail
  • Training
DOE White Seal
  • Terms of Use/Privacy

Managed by Triad National Security, LLC for the U.S. Dept. of Energy’s NNSA

Copyright 2026 Triad National Security, LLC. All Rights Reserved.

Learn about the Department of Energy’s Vulnerability Disclosure Program