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Laboratory partners with OpenAI to advance national security

For the first time ever, the latest reasoning models from OpenAI will be used for energy and national security applications on Los Alamos’s Venado supercomputer

June 11, 2025

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Los Alamos National Laboratory has entered a partnership with OpenAI to install its latest o-series models — capable of expert reasoning for a broad span of complex scientific problems — on the Lab’s Venado supercomputer, which uses NVIDIA GH200 Grace Hopper Superchips, to conduct national security research. 

“As threats to the nation become more complex and more pressing, we need new approaches and advanced technologies to preserve America’s security,” said Laboratory director Thom Mason.  “Artificial intelligence models from OpenAI will allow us to do this more successfully, while also advancing our scientific missions to solve some of the nation’s most important challenges.” 

The Venado machine will be moved to a secure, classified network where it will be a shared resource for researchers from Los Alamos, Lawrence Livermore, and Sandia national labs. 

> Read the full story in our News section

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