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Isotope R&D and Production

Isotope production and applications

Isotopes produced at Los Alamos National Laboratory are saving lives, advancing cutting-edge research and keeping the U.S. safe.

The LANL Isotope Program utilizes unique capabilities to produce radioisotopes that are in short supply. The Isotope Production Facility (IPF), a 100 MeV proton bombardment station located at the Los Alamos Neutron Science Center (LANSCE), is a premier facility able to conduct high current irradiations for large scale production, as well as delicate, low current experimental work. The Program also maintains a robust hot cell facility for isotope processing, as well as a glovebox line within the LANL plutonium facility.

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Los Alamos National Laboratory Isotope Program receives funding from the U.S. Department of Energy Isotope R&D and Production Program (DOE Isotope Program), managed by the Office of Science, as part of a suite of national laboratories and universities focused on isotope R&D and production. The mission of the DOE Isotope Program is to produce and distribute stable and radioactive isotopes for research and applications that are in short supply and critical to the prosperity and security of the Nation. The DOE Isotope Program supports isotope production, R&D on isotope production techniques, workforce development, and reduction of U.S. dependency on foreign supply chains.

Those interested in purchasing stable or radioactive isotopes from the DOE Isotope Program should contact the National Isotope Development Center.

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Isotopes produced at IPF are critical for medical diagnosis and disease treatment. These positron emission tomography images were made possible using isotopes produced at LANL.

LANL-produced isotopes for medical, industrial & research applications

  • Actinium-225 (225Ac), used for targeted alpha therapy (TAT)

  • Americium-241 (241Am), used in smoke detector and for oil/gas exploration

  • Sodium-22 (22Na), used as a source for positron emission tomography

  • Arsenic-73 (73As), used for environmental research

  • We have partnered with the TRIUMF facility to receive irradiated targets that are processed for aluminum-26 (26Al) and silicon-32 (32Si)

  • Additional isotopes can be produced on demand

We have partnered with the TRIUMF facility to receive irradiated targets that are processed for aluminum-26 (26Al) and silicon-32 (32Si).

Description of R&D Activities

The LANL Isotope Program is also engaged in the development of new isotopes for application in the fields of medicine, fundamental nuclear physics, national security, environmental science and industrial applications. Los Alamos National Laboratory possesses a unique combination of facilities and staff expertise that enable the production, purification and distribution of a variety of isotopes and associated applications. See current list of publications and local/national new highlights below for more details.

NEWS HIGHLIGHTS

LA-UR-22-20988

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Contact

  • Program Manager
  • Dr. Kirk Rector
  • Los Alamos National Laboratory Los Alamos, NM 87545
  • Email
  • 505-606-8012

Video

Isotope Cancer Treatment Research at LANL

Los Alamos National Laboratory has produced medical isotopes for diagnostic and imaging purposes for more than 30 years. Now LANL researchers have branched out into isotope cancer treatment studies.

Relationship statement between the DOE IP and LANL

Los Alamos National Laboratory Isotope Program receives funding from the U.S. Department of Energy Isotope R&D and Production Program (DOE Isotope Program), managed by the Office of Science, as part of a suite of national laboratories and universities focused on isotope R&D and production. The mission of the DOE Isotope Program is to produce and distribute stable and radioactive isotopes for research and applications that are in short supply and critical to the prosperity and security of the Nation. The DOE Isotope Program supports isotope production, R&D on isotope production techniques, workforce development, and reduction of U.S. dependency on foreign supply chains. Those interested in purchasing stable or radioactive isotopes from the DOE Isotope Program should contact the National Isotope Development Center. (This is language provided to us by the DOE SC Isotope R&D and Production Office)

Description of Facilities

The LANL Isotope Program utilizes unique capabilities to produce radioisotopes that are in short supply. The Isotope Production Facility (IPF), a 100 MeV proton bombardment station located at the Los Alamos Neutron Science Center (LANSCE), is a premier facility able to conduct high current irradiations for large scale production, as well as delicate, low current experimental work. The Program also maintains a robust hot cell facility for isotope processing, as well as a glovebox line within the LANL plutonium facility. (no change from what is currently on the web)

Organizational and Staff Information

Dr. Kirk Rector

Program Manager for the LANL Isotope Program

Mail Stop J515

Los Alamos, NM 87545-1663

Email: kdr@lanl.gov

Office: 505-606-8012

Cell: 505-695-6991

Resources

  • DOE Isotope Research & Development and Production
  • National Isotope Development Center

Automation of Nuclear Chemistry Processes Leads to More Efficient Production of Astatine for Cancer Therapy

Deep Learning Model Overcomes the Challenge of Real-World Measurements of Isotope Production Target Cooling Systems

Combating drug resistant infections with radioisotopes

New Imaging Isotope Meets Promising Therapy Isotopes

Harnessing the Power of Uranium to Treat Disease

Ordinary people, extraordinary times

The paradox of using radionuclides to treat disease

Tri-Lab effort ramps up to actinium-225 production to support clinical trials

Targeted radioactive treatment offers promise in cancer treatment

New approach yields high-purity radium for medical applications

Groundbreaking Cancer Therapy Clinical Trial with U.S. Department of Energy’s Accelerator-Produced Actinium-225 Set to Begin this Summer