Use of optical spectroscopies, including (resonance) Raman and magnetic circular dichroism, electron paramagnetic and nuclear magnetic resonance spectroscopies.
Handling, preparation, and analysis of biological samples, with special emphasis on spectroscopic studies of metalloenzymes.
Synchrotron based X-ray spectroscopies, including X-ray absorption and XAFS. Experience with the analysis of a wide variety of inorganic, organometallic, and metalloenzyme samples by these techniques.
Handling, characterization, and preparation of radioactive materials, including both long- and short- lived isotopes and samples of high activity.
Synthesis and characterization of organic, inorganic, and organometallic compounds.
Experience with computational chemistry methodologies, including density functional theory (DFT), ab initio, and molecular mechanics (MM). Emphasis on calculation of spectroscopic properties of inorganic and bioinorganic systems.
Education
Doctor of Philosophy, Chemistry
University of New Mexico
2015
Bachelor of Science, Chemistry
University of Northern Colorado
2007
Positions
2015 - Present | Seaborg Postdoctoral Fellow. Inorganic, Isotope, and Actinide Chemistry Group
Awards
2015 Seaborg Postdoctoral Fellowship. Los Alamos National Laboratories.
2015 Dissertation Defense and Manuscript Approved with Distinction. University of New Mexico.
2014 Smith-Dow Graduate Fellowship. University of New Mexico.
2007 Outstanding Chemistry Major. University of Northern Colorado.
Professional Societies
American Chemical Society
Publications
Kirk, M.L. and Stein, B.W. Molybdenum Enzymes, in Comprehensive Inorganic Chemistry II. 2013. doi:10.1016/B978-0-08-097774-4.00316-8.
Cary, S.K.; Ferrier, M.G.; Baumbach, R.E.; Silver, M.A.; Pacheco J.L.; Kozimor S.A.; La Pierre, H.S.; Stein, B.W., Arico, A.A.; Gray, D.L.; Albrecht-Schmitt, T.E. Monomers, Dimers, and Helices: Com- plexities of Cerium and Plutonium Phenanthrolinecarboxylates. Inorg. Chem. 2016, 55, 4373–4380 doi:10.1021/acs.inorgchem.6b00077.
Gao, J.; Stein, B.W.; Thomas, A.K.; Garcia J.A.; Yang, J.; Kirk, M.L.; Grey, J.K. Enhanced Charge Transfer Doping Efficiency in J-Aggregate Poly (3-hexylthiophene) Nanofibers. J. Phys. Chem. C 2015, 119, 16396–16402. doi:10.1021/acs.jpcc.5b05191.
Shultz, D.; Stasiw, D.; Kirk, M.; Zhang, J.; Stein, B.; Dangi, R.; Sommer, R.; Wojtas, L. Determining the Conformational Landscape of σ and π Coupling Using para-Phenylene and “Aviram–Ratner" Bridges. J. Am. Chem. Soc. 2015, 137, 9222–9225.
Stein, B.W.; Kirk, M.L. Electronic structure contributions to reactivity in xanthine oxidase family enzymes. J. Biol. Inorg. Chem. 2014, 20, 183–194. doi:10.1007/s00775-014-1212-8.
Cutsail, G.E.; Stein, B.W.; Subedi, D.; Smith, J.M.; Kirk, M.L.; Hoffman, B.M. EPR, ENDOR, and Electronic Structure Studies of the Jahn-Teller Distortion in an Fe(V) Nitride. J. Am. Chem. Soc. 2014, 136, 12323–12336. doi:10.1021/ja505403j. JACS Spotlight.
Stein, B.W.; Kirk, M.L. Frontier Molecular Orbital Contributions to CO Oxidation in Mo-Cu Carbon Monoxide Dehydrogenase. Chem. Commun. 2014, 50, 1104–1106. doi:10.1039/C3CC47705C.
Kirk, M.L.; Shultz, D.A., Stasiw, D.E.; Habel-Rodriguez, D.; Stein, B.; Boyle, P.D. Electronic and Exchange Coupling in a Cross-Conjugated D-B-A Biradical: Mechanistic Implications for Quantum Interference Effects. J. Am. Chem. Soc. 2013, 135, 14713–14725. doi:10.1021/ja405354x.
Barry, B.M.; Stein, B.W.; Larsen, C.A.; Wirtz, M.N.; Geiger, W.E.; Waterman, R.; Kemp, R.A. Metal Complexes (M = Zn, Sn, and Pb) of 2-Phosphinobenzenethiolates: Insights into Ligand Folding and Hemilability. Inorg. Chem. 2013, 52, 9875–9884 doi:10.1021/ic400990n.
Rothery, R.A.; Stein. B.; Solomonson, M.; Kirk, M.L.; Weiner, J.H. Pyranopterin conformation defines the function of molybdenum and tungsten enzymes. P. Natl. Acad. Sci. USA 2012, 109, 14773–14778. doi:10.1073/pnas.1200671109.
O’Halloran, K.P. et. Al. Revisiting the Polyoxometalate-Based Late-Transition-Metal-Oxo Complexes: The “Oxo Wall” Stands. Inorg. Chem. 2012, doi:10.1021/ic2008914.
Mtei, R.P.; Lyashenko, G; Stein B.; Rubie, N.; Hille, R.; Kirk, M.L. Spectroscopic and Electronic Struc- ture Studies of a Dimethyl Sulfoxide Reductase Catalytic Intermediate: Implications for Electron-and Atom-Transfer Reactivity. J. Am. Chem. Soc. 2011, 133, 9762–9774. doi:10.1021/ja109178q.
Sempombe, B.; Stein, B.; Kirk M.L. Spectroscopic and Electronic Structure Studies Probing Cova- lency Contributions to C–H Bond Activation and Transition-State Stabilization in Xanthine Oxidase. Inorg. Chem. 2011, 50, 10919–10928 doi:10.1021/ic201477n.
Mtei, R.P.; Perera, E.; Mogesa, B.; Stein, B.; Basu, P.; Kirk, M.L. A Valence Bond Description of Dizwitterionic Dithiolene Character in an Oxomolybdenum-Bis(dithione) Complex. Eur. J. Inorg. Chem. 2011, 5467–5470 doi:10.1002/ejic.201101084.