Los Alamos National LaboratoryBiosurveillance Gateway
Diagnostics, predictive modelling, and decision support for global and national security
Biosurveillance in Action
Los Alamos National Laboratory is applying biosurveillance expertise to the COVID-19 pandemic.
Current COVID-19 Projects
Diagnostics and Genomics
- Using genomics to validate publicly available SARS-CoV-2 assays and to identify why some produce false negatives. COVID-19 Genome Analytics website
- FDA-CLIA registered COVID-19 testing facility to support surge capacity diagnostic testing.
- Developing high-affinity antibody pairs for advanced diagnostic tools.
- Testing several commercially available and lab-made viral transport media to facilitate the testing supply chain.
- Providing bioinformatics expertise and support to partner labs worldwide that are processing COVID-19 samples in their own countries.
- Developing new tests that could screen for multiple respiratory pathogens at once.
Predictive Modeling
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Forecasting Confirmed Cases and Deaths for COVID-19. COVID-19 Forecasted Case Data website
- Quantifying how the SARS-CoV-2 virus behaves in the host organism.
- Using bioinformatics and modeling to track the diversity of the pathogen and how it is evolving in the pandemic.
Decision Support
- Developing models of various mitigation strategies to inform decision makers.
- Modeling hospital/healthcare surge capacity in response to COVID-19.
- Using models to evaluate critical healthcare supply chains.
Vaccines and Countermeasures
- Developing a T-cell response vaccine for SARS-CoV-2.
- Investigating the interaction between SARS-CoV-2 and human receptors to develop lung-protective therapies.
- Design and synthesis of surface proteins for drug studies.
- Synthesis of anti-viral drugs for the treatment of COVID-19.
- Structural and computational identification of potential drug targets.
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