Los Alamos National LaboratoryBiosurveillance Gateway
Diagnostics, predictive modelling, and decision support for global and national security

Biosurveillance in Action

Los Alamos National Laboratory is applying biosurveillance expertise to the COVID-19 pandemic.

Contact Us  

  • Media Contact
  • Nancy Ambrosiano
  • (505) 699-1149
  • Email
  • National Security and Defense Program Office
  • Kirsten Taylor-McCabe
  • (505) 665-0634
  • Email

Current COVID-19 Projects

Diagnostics and Genomics

  • COVID-19 Genome Analytics website for sequence to genome tools, phylogeny-informed assay validation, and geographic analytics of COVID-19 cases.
  • SARS-CoV-2 sequence analysis pipeline for analyses and tools for exploring accruing mutations in the Spike protein of SARS-CoV-2.
  • Operating an FDA-CLIA registered COVID-19 diagnostic testing facility for LANL personnel and LANL subcontractor  personnel.
  • Developing high-affinity antibody pairs for advanced diagnostic tools.
  • Evaluating various supply chain elements (viral transport media, assay kits, pooling strategies, reagents) to enhance diagnostic testing.
  • Providing bioinformatics expertise and support to partner labs worldwide that are processing COVID-19 samples in their own countries.
  • Developing new tests that could screen for multiple respiratory pathogens at once.

Predictive Modeling and Decision Support

  • The Global Disease Modeling & Forecasting Center (pdf) combines Los Alamos capabilities and key partnerships to develop, validate, and operationalize epidemiological models to combat infectious diseases.
  • COVID-19 Forecasted Case Data website for tracking confirmed COVID-19 cases and deaths and forecasting future spread.
  • Evaluating testing and diagnostic sensitivity and providing decision support analysis for testing diagnostics, strategy, and uncertainty at the metropolitan level—using Modeling Epidemics for Decision support and Infrastructure ANalysis (MEDIAN).
  • Working with three other National Laboratories to provide situational awareness, predictive modeling, and a visualization portal to characterize the spread of COVID-19 across the United States.
  • Quantifying how the SARS-CoV-2 virus behaves in the host organism.
  • Using bioinformatics and modeling to track the diversity of the pathogen and how it is evolving in the pandemic.
  • Developing models of various mitigation strategies to inform decision makers at the state and local level.
  • Modeling hospital/healthcare surge capacity in response to COVID-19.
  • Using models to evaluate critical healthcare supply chains.

Vaccines and Countermeasures

  • Developing a T-cell response vaccine for SARS-CoV-2.
  • Investigating the interaction between SARS-CoV-2 and human receptors to develop lung-protective therapies.
  • Designing and synthesizing surface proteins for drug studies.
  • Synthesizing compounds for anti-viral drugs for the treatment of COVID-19.
  • Identifying potential drug targets through structural and computational studies. 

National Virtual Biotechnology Laboratory (NVBL)

Several LANL biosurveillance projects are coordinated with and funded by the Department of Energy NVBL

Submit a request to learn more about LANL capabilities or to contact scientists