Center for Integrated Nanotechnologies

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James Henry Werner

Jim Werner

Phone (505) 667-8842


  • Biosciences
  • Single cell genomics
  • Biomaterials
  • Optical imaging and tomography of biological tissue
  • Materials
  • Microfabrication
  • Nanotechnology
  • Optics and fiber optics
  • Nanoscale (in time and space) spectroscopies
  • Biological assemblies
  • Center for Integrated Nanotechnologies (CINT)
  • CINT
  • Structure Measurements
  • Property Measurements
  • Function/Response Measurements
  • Characterization





Instrument Development


B.S., Applied Physics, California Institute of Technology, 1992

M.S., Applied Physics, Cornell University, 1994

Ph.D., Applied Physics, Cornell University, 1998


Professional Appointments

Deputy Group Leader, Center for Integrated Nanotechnologies, 8/2017-present

Acting Group Leader, Center for Integrated Nanotechnologies, 3/2017-8/2017

Acting Deputy Group Leader, Center for Integrated Nanotechnologies, 10/2016-3/2017

Technical Staff Member, 3/2001 - 10/2016

Postdoctoral Research Associate, 1998 - 2001


Professional Societies

Biophysical Society

American Chemical Society

American Physical Society



Fellow, American Physical Society, 2016

Los Alamos Distinguished Patent Award, 2011

R&D 100 Award “NanoCluster Beacons” , 2011

Los Alamos Postdoctoral Distinguished Mentor Award, 2011

R&D 100 Award “3D Tracking Microscope” (2008)

Hertz Foundation Fellowship (1992-1997)



Compositions and methods for detecting single nucleotide polymorphisms H Yeh, J Werner, JS Martinez - US Patent 9,499,866, 2016

Probe and method for DNA detection H Yeh, JH Werner, JK Sharma, JS Martinez - US Patent 8,476,014, 2013

3 Dimensional Imaging at Nanometer Resolutions JH Werner, AP Shreve, PM Goodwin - US Patent 7,667,045, 2010

Apparatus and Method for Tracking a Molecule or Particle in 3 Dimensions JH Werner, GA Lessard, PM Goodwin - US Patent 7,498,551, 2009






"DNA Templated Metal Nanoclusters: From Emergent Properties to Unique Applications," Y. Chen, M.E. Phipps, J.H. Werner, S. Chakraborty, J.S. Martinez, Accounts of Chemical Research (2018) [DOI: 10.1021/acs.accounts.8b00366].

"Multicolor Three-Dimensional Tracking for Single-Molecule Fluorescence Resonance Energy Transfer Measurements," A. M. Keller, M.S. DeVore, D. G. Stich, D. M. Vu,T. Causgrove, and James H. Werner, Analytical Chemistry 90, 6109−6115 (2018).

"Light-sheet microscopy by confocal line scanning of dual-Bessel beams," Zhang, P., Phipps, ME, Goodwin, P, and Werner, J., Journal of Biomedical Optics 21(10), 100502 (2016).

"Note: Time-gated 3D single quantum dot tracking with simultaneous spinning disk imaging," DeVore, M, Stich, D, Keller, A, Cleyrat, C, Phipps, M, Hollingsworth, J, Lidke, D, Wilson, B, Goodwin, P and Werner, J, Review of Scientific Instruments 86, 126102, (2015).

"3Dimensional Tracking of Nonblinking ‘Giant’Quantum Dots in Live Cells," Keller, AM, Ghosh, Y, DeVore, MS, Phipps, ME, Stewart, MH, Wilson, BS, Lidke, DS, Hollingsworth, JA and Werner, JH, Advanced Functional Materials 24, 4796-4803, (2014).

"Fast, super resolution imaging via Bessel-beam stimulated emission depletion microscopy," Zhang, P, Goodwin, P and Werner, J, Optics Express 22, 12398-12409, (2014).