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Brian M. Patterson

Brian Patterson

Phone (505) 500-2726


  • Materials
  • Dynamic loading
  • Polymer characterization techniques
  • Polymer science
  • Electron microscopy
  • X-ray spectroscopy and imaging
  • Soft and biological materials
  • Science of Signatures - Remote and Standoff Sensing
  • X-rays
  • Radiography
  • Hyperspectral for infrared, VIS, and UV
  • Image analysis
  • Science of Signatures - In Situ Measurements
  • Electron microscopy
  • Scanned probe microscopies
  • Weapons Science and Engineering
  • Stockpile stewardship
  • Material fabrication and characterization
  • Stockpile surveillance
  • ICF and HED targets
  • X-ray radiographic simulation and analysis
  • Materials
  • In-situ Load-Stress/Strain X-ray Characterization


Brian M. Patterson, Ph.D. is an analytical chemist specializing in materials characterization and capability development within the Engineered Materials Group of the Materials Science and Technology Division at Los Alamos National Laboratory. He has 17 years of analytical experience and uses these technologies to answer challenging materials science questions of importance to both the global security and the nuclear weapons complex. Additionally he has several years of line management experience at the team leader level to communicate priorities up and down the management line, oversee budgets, and observe performance. Finally, he serves on the editorial board of Microscopy Today. Before returning to graduate school, he was a high school science teacher (Chemistry, Physics and General Science).

Core Competencies:

  • Materials Science Characterization, Instrumentation Development, In situ Characterization
  • Technical Leadership, Proposal writing
  • Adaptability, Teaming, People skills
  • Communication, Technical writing, Program Development, Presentations

Materials Characterization Techniques:

  • Laboratory based micro- and nano-scale X-ray tomography
  • Synchrotron based micro-scale tomography
  • Dynamic in-situ tomography
  • X-ray fluorescence
  • Hyperspectral imaging
  • Infrared microspectroscopy, ATR, imaging
  • Scanning Electron Microscopy, EDS/Backscatter


Ph.D., 2004, Analytical Chemistry, Miami University, Oxford, OH

B.Ed., 1997, Certification in High School Chemistry, Physics, Comprehensive Science and General Science, University of Toledo, Toledo, OH


LANL Positions

2013- Team Leader, Characterization and Forensics Team, Polymers and Coatings Group

2006- Scientist, Materials Science and Technology Division

2004-2006, Post-doc, Chemistry Division


Professional Societies






2013 LANL Pollution Prevention Silver Star

2012 Distinguished Performance Award, Los Alamos National Explosives Engineering Security Sciences Center Team

2007, Defense Programs Award of Excellence



Non-provisional Patent Application #104964 “Method and Apparatus for Internal Reflection Imaging”, Patterson, Brian M.; Havrilla, George J.; USPTO 2006.



Peer Reviewed Publications:

1.      Smith, D. H.; Bicknell, J.; Jorgensen, L.; Patterson, B. M.; Cordes, N. L.; Tsukrov, I.; Knezevic, M., Microstructure and mechanical behavior of direct metal laser sintered Inconel alloy 718. Materials Characterization 2016, 113, 1-9.

2.      Randolph, R.; Oertel, J. A.; Schmidt, D. W.; Lee, M. N.; Patterson, B. M.; Henderson, K.; Hamilton, C. E., Process Development and Micro-Machining of MARBLE Foam-Cored Rexolite Hemi-Shell Ablator Capsules. Fusion Sci. and Technol. 2016, 70 (2), 230-236.

3.      Patterson, B. M.; Cordes, N. L.; Henderson, K.; Williams, J.; Stannard, T.; Singh, S. S.; Ovejero, A. R.; Xiao, X.; Robinson, M.; Chawla, N., In situ X-ray synchrotron tomographic imaging during the compression of hyper-elastic polymeric materials. Journal of Material Science 2016, 51 (1), 171-187.

4.      Patterson, B. M.; Cordes, N. L.; Henderson, K.; Mertens, J. C. E.; Clarke, A. J.; Hornberger, B.; Merkle, A.; Etchin, S.; Tkachuk, A.; Leibowitz, M.; Trapp, D.; Qiu, W.; Zhang, B.; Bale, H.; Lu, X.; Hartwell, R.; Withers, P. J.; Bradley, R. S., In Situ Laboratory-Based Transmission X-Ray Microscopy and Tomography of Material Deformation at the Nanoscale. Exp Mech 2016, 1-13.

5.      Kort-Kamp, W. J. M.; Cordes, N. L.; Ionita, A.; Glover, B. B.; Higginbotham Duque, A. L.; Perry, W. L.; Patterson, B. M.; Dalvit, A. R.; Moore, D. S., Microscale Electromagnetic Heating in Heterogeneous Energetic Materials Based on X-ray Computed Tomography. Physical Review Applied 2016, 5 (4), 044008.

6.      Holesinger, T. G.; Carpenter, J. S.; Lienert, T. J.; Patterson, B. M.; Papin, P. A.; Swenson, H.; Cordes, N. L., Characterization of an Aluminum Alloy Hemispherical Shell Fabricated via Direct Metal Laser Melting. JOM 2016, 1-12.

7.      McIntosh, K. G.; Cordes, N.; Patterson, B.; Havrilla, G., Laboratory-based characterization of Pu in soil particles using micro-XRF and 3D confocal XRF. Journal of Analytical Atomic Spectrometry 2015.

8.      Livescu, V.; Bingert, J. F.; Liu, C.; Lovato, M. L.; Patterson, B. M., Biaxial deformation in high purity aluminum. Materials Science and Engineering: A 2015, 648, 330-339.

9.      Imhoff, S. D.; Gibbs, P. J.; Katz, M. R.; Ott Jr, T. J.; Patterson, B. M.; Lee, W. K.; Fezzaa, K.; Cooley, J. C.; Clarke, A. J., Dynamic evolution of liquid–liquid phase separation during continuous cooling. Materials Chemistry and Physics 2015, 153 (0), 93-102.

10.    Hornberger, B.; Bale, H.; Merkle, A.; Feser, M.; Harris, W.; Etchin, S.; Leibowitz, M.; Qiu, W.; Tkachuk, A.; Gu, A.; Bradley, R. S.; Lu, X.; Withers, P. J.; Clarke, A.; Henderson, K.; Cordes, N.; Patterson, B. M. In X-ray microscopy for in situ characterization of 3D nanostructural evolution in the laboratory, Proceedings of SPIE - The International Society for Optical Engineering, 2015.

11.    Cordes, N. L.; Seshadri, S.; Havrilla, G.; Yuan, X.; Feser, M.; Patterson, B. M., Three Dimensional Subsurface Elemental Identification of Minerals using Confocal Micro X-ray Fluorescence and Micro X-ray Computed Tomography. Spectrochimica Acta Part B: Atomic Spectroscopy 2015, 103-104.

12.    Brown, E. N.; Ramos, K. J.; Dattelbaum, D. M.; Jensen, B. J.; Iverson, A. J.; Carlson, C. A.; Fezzaa, K.; Gray, G. T.; Patterson, B. M.; Trujillo, C. P.; Martinez, D. T.; Pierce, T. H.; Furmanski, J., In Situ and Postmortem Measures of Damage in Polymers at High Strain-Rates. In Dynamic Behavior of Materials, Volume 1: Proceedings of the 2014 Annual Conference on Experimental and Applied Mechanics, Song, B.; Casem, D.; Kimberley, J., Eds. Springer International Publishing: Cham, 2015; pp 53-59.

13.    Brown, A. D.; Pham, Q.; Peralta, P.; Luo, S. N.; Patterson, B. M.; Byler, D.; Koskelo, A.; Xiao, X., Correlations Between Spall Damage Mode Preference and Microstructure in Shocked Polycrystalline Copper: A 3-D X-Ray Tomography Study. J. dynamic behavior mater. 2015, 1-9.

14.    Patterson, B. M.; Henderson, K. C.; Gibbs, P. J.; Imhoff, S. D.; Clarke, A. J., Laboratory micro- and nanoscale X-ray tomographic investigation of Al–7at.%Cu solidification structures. Materials Characterization 2014, 95 (0), 18-26.

15.    Patterson, B. M.; Henderson, K.; Gilbertson, R. D.; Tornga, S.; Cordes, N. L.; Chavez, M. E.; Smith, Z., Morphological and performance Measures of Polyurethane Foams using X-ray CT and Mechanical Testing. Microscopy and Microanalysis 2014, 95, 18-26.

16.    Fensin, S. J.; Escobedo, J. P.; Gray, G. T.; Patterson, B. M.; Trujillo, C. P.; Cerreta, E. K., Dynamic damage nucleation and evolution in multiphase materials. Journal of Applied Physics 2014, 115, 203516.

17.    Escobedo, J. P.; Cerreta, E. K.; Dennis-Koller, D.; Patterson, B. M.; Bronkhorst, C. A., Influence of shock loading kinetics on the spall response of copper. Journal of Physics: Conference Series 2014, 500 (PART 11).

18.    Dattelbaum, D. M.; Coe, J. D.; Kiyanda, C. B.; Gustavsen, R. L.; Patterson, B. M., Reactive, anomalous compression in shocked polyurethane foams. Journal of Applied Physics 2014, 115 (174908).

19.    Cordes, N. L.; Havrilla, G. J.; Usov, I. O.; Obrey, K. A.; Patterson, B. M., Non-destructive elemental quantification of polymer-embedded thin films using laboratory based X-ray techniques. Spectrochimica Acta Part B: Atomic Spectroscopy 2014, 101 (0), 320-329.

20.    Brown, E. N.; Furmanski, J.; Ramos, K. J.; Dattelbaum, D. M.; Jensen, B. J.; Iverson, A. J.; Carlson, C. A.; Fezzaa, K.; Gray III, G. T.; Patterson, B. M.; Trujillo, C. P.; Martinez, D. T.; Pierce, T. H., High-density polyethylene damage at extreme tensile conditions. Journal of Physics: Conference Series 2014, 500 (11), 112011.

21.    Patterson, B. M.; Henderson, K.; Smith, Z., Measure of morphological and performance properties in polymeric silicone foams by X-ray tomography. Journal of Materials Science 2013, 48 (5), 1986-1996.

22.    Obrey, K.; Schmidt, D.; Hamilton, C.; Capelli, D.; Williams, J.; Randolph, R.; Fierro, F.; Hatch, D.; Havrilla, G.; Patterson, B., Advances in target design and fabrication for experiments on NIF. EPJ Web of Conferences 2013, 59, 12001.

23.    Holesinger, T. G.; Baca, F. J.; Kennison, J. A.; Coulter, J. Y.; Patterson, B. M.; Marken, K. R., Microstructure-Based Model for Current Flow in Bi-2212 Round Wire Conductors. Applied Superconductivity, IEEE Transactions on 2013, 23 (3), 6400305-6400305.

24.    Hehlen, M. P.; Parker, G. R.; Novak, A. M.; Rae, P.; Rivera, G.; Schmidt, D. W.; Henderson, K. C.; Patterson, B. M.; Smilowitz, L. B. In Fiber-Optic Point Measurement of High Pressures in Thermal Explosions, CLEO: 2013, San Jose, California, 2013/06/09; Optical Society of America: San Jose, California, 2013; p CTu2H.6.

25.    Clarke, A.; Imhoff, S.; Gibbs, P.; Cooley, J.; Morris, C.; Merrill, F.; Hollander, B.; Mariam, F.; Ott, T.; Barker, M.; Tucker, T.; Lee, W.-K.; Fezzaa, K.; Deriy, A.; Patterson, B.; Clarke, K.; Montalvo, J.; Field, R.; Thoma, D.; Smith, J.; Teter, D., Proton Radiography Peers into Metal Solidification. Scientific Reports 2013, 3 (2020), 1-6.

26.    Clarke, A.; Imhoff, S.; Cooley, J.; Patterson, B.; Lee, W.-K.; Fezzaa, K.; Deriy, A.; Tucker, T.; Katz, M. R.; Gibbs, P.; Clarke, K.; Field, R. D.; Thoma, D. J.; Teter, D. F., X-ray imaging of Al-7at.% Cu during melting and solidification. Emerging Materials Research 2013, 2 (2), 90-98.

27.    Brown, A.; Krishnan, K.; Wayne, L.; Peralta, P.; Luo, S. N.; Byler, D.; Patterson, B., 3-D Characterization of Global and Local Microstructural Effects on Spall Damage in Shock Loaded FCC Metals: Experimental and Modeling. AMECE 2013 Conf. Proc. 2013.

28.    Patterson, B. M.; Obrey, K. A. D.; Hamilton, C. E.; Havrilla, G. J., Three- Dimensional Density measurements of Ultra Low Density materials by X-ray Scatter Using Confocal Micro X-ray Fluorescence Spectroscopy. X-Ray Spectrometry 2012, 41 (4), 253-258.

29.    Patterson, B. M.; Escobedo-Diaz, J. P.; Dennis-Koller, D.; Cerreta, E. K., Dimensional Quantification of Embedded Voids or Objects in Three Dimensions Using X-ray Tomography. Microscopy and Microanalysis 2012, 18 (2), 390-398.

30.    Grano, A. J.; Sayler, F. M.; Genau, A.; Graves, K. L.; Patterson, B. M.; Wang, Y.; Smått, J.-H.; Bakker, M. G., X-ray and FIB Tomography of Extremely High Surface Area Nanostructured Hollow Fiber Membranes. MRS Proceedings 2012, 1421, 41-42.

31.    Escobedo, J.; Cerreta, E.; Dennis-Koller, D.; Patterson, B.; Lebensohn, R.; Bronkhorst, C. In Effects of microstructure and shock loading conditions on the damage behavior of polycrystalline copper, EPJ Web of Conferences, 2012; p 02008.

32.    Dennis-Koller, D.; Escobedo-Diaz, J. P.; Cerreta, E.; Bronkhorst, C. A.; Hansen, B.; Lebensohn, R.; Mourad, H.; Patterson, B.; Tonks, D., Controlled shock loading conditions for micrstructural correlation of dynamic damage behavior. AIP Conference Proceedings 2012, 1426, 1325.

33.    Dennis-Koller, D.; Escobedo-Diaz, J.; Cerreta, E.; Bronkhorst, C.; Hansen, B.; Lebensohn, R.; Mourad, H.; Patterson, B.; Tonks, D., Isolation of kinetic and spatial properties of uni-axial dynamic tensile loading of OFHC copper. EPJ Web of Conferences 2012, 26 (01040).

34.    Dattelbaum, D. M.; Gustavsen, R. L.; Sheffield, S. A.; Stahl, D. B.; Scharff, R. J.; Rigg, P. A.; Furmanski, J.; Orler, E. B.; Patterson, B.; Coe, J. D., The dynamic response of carbon fiber-filled polymer composites. EPJ Web of Conferences 2012, 26, 02007.

35.    Patterson, B. M.; Obrey, K. A.; Havrilla, G. J., Further Characterizations of Sputtered Copper Beryllium Capsules Using Confocal Micro X-ray Fluorescence. Fusion Sci. and Technol. 2011, 59 (1), 121-125.

36.    Hamilton, C. E.; Honnell, D.; Patterson, B. M.; Schmidt, D. W.; DeFriend Obrey, K. A., Incorporation of tracer elements within aerogels and CH foams. Fusion Sci. and Technol. 2011, 59 (1), 194-198.

37.    Escobedo, J. P.; Dennis-Koller, D.; Cerreta, E. K.; Patterson, B. M.; Bronkhorst, C. A.; Hansen, B. L.; Tonks, D.; Lebensohn, R. A., Effects of grain size and boundary structure on the dynamic tensile response of copper. Journal of Applied Physics 2011, 110 (3), 033513.

38.    Thompson, D. G.; Brown, G. W.; Olinger, B.; Mang, J. T.; Patterson, B. M.; De Luca, R.; Hagelberg, S., The Effects of TATB Rachet Growth on PBX-9502. Propellents, Explosives and Pyrotechnics 2010, 35 (6), 507-513.

39.    Patterson, B. M.; Hamilton, C. E., Dimensional Standard for Micro X-ray Computed Tomography. Analytical Chemistry 2010, 82 (20), 8537-8543.

40.    Patterson, B. M.; Cerreta, E. K.; Dennis-Koller, D.; Bronkhorst, C. A.; Hansen, B. L., Characterization of Dynamic Damage of Copper Targets using X-ray Micro Tomography. Microscopy and Microanalysis 2010, 16 (S2), 726-727.

41.    Patterson, B. M.; Campbell, J.; Havrilla, G. J., Integrating 3D images using laboratory-based micro X-ray computed tomography and confocal X-ray fluorescence techniques. X-Ray Spectrometry 2010, 39 (3), 184-190.

42.    Obrey, K. A. D.; Schmidt, D.; Patterson, B. M.; Day, R. D.; Valdez, A. C.; Capelli, D.; Perea, R.; Randolph, R.; Hatch, D.; Garcia, F., Improvements in ICF target fabrication through high precision assembly and nondestructive characterization. Journal of Physics: Conference Series 2010, 244 (3), 032040.

43.    Thompson, D. G.; Brown, G. W.; Mang, J. T.; De Luca, R.; Patterson, B.; Hagelberg, S., Characterizing the Effects of Ratchet Growth on PBX-9502. Shock Compression of Condensed Matter 2009, 1195, 388-391.

44.    Patterson, B. M.; DeFriend, K. A.; Havrilla, G. J.; Nikroo, A.; Haung, H., Nondestructive investigations of a copper- and argon- doped sputtered beryllium capsule using X-rays in three dimensions. Fusion Sci. and Technol. 2009, 55 (4), 417-423.

45.    Devlin, D.; Jarvinen, G.; Patterson, B.; Pattillo, S.; Valdez, J.; Liu, X.-Y.; Phillips, J., New generation nuclear fuel structures: Dense particles in selectively soluble matrix. Journal of Nuclear Materials 2009, 394 (2), 190-196.

46.    DeFriend Obrey, K. A.; Day, R. D.; Hatch, D.; Espinoza, B. F.; Feng, S.; Patterson, B. M., Manufacturing complex silica aerogel target components. Fusion Sci. and Technol. 2009, 55 (4), 490-498.

47.    Wilson Jr, K. V.; Patterson, B. M.; Phillips, J., Microbalance study of the corrosion kinetics of lithium hydride by water. Journal of Nuclear Materials 2008, 374 (1), 229-240.

48.    Tandon, L.; Hastings, E.; Banar, J.; Barnes, J.; Beddingfield, D.; Decker, D.; Dyke, J.; Farr, D.; FitzPatrick, J.; Gallimore, D.; Garner, S.; Gritzo, R.; Hahn, T.; Havrilla, G.; Johnson, B.; Kuhn, K.; LaMont, S.; Langner, D.; Lewis, C.; Majidi, V.; Martinez, P.; McCabe, R.; Mecklenburg, S.; Mercer, D.; Meyers, S.; Montoya, V.; Patterson, B.; Pereyra, R. A.; Porterfield, D.; Poths, J.; Rademacher, D.; Ruggiero, C.; Schwartz, D.; Scott, M.; Spencer, K.; Steiner, R.; Villarreal, R.; Volz, H.; Walker, L.; Wong, A.; Worley, C., Nuclear, chemical, and physical characterization of nuclear materials. Journal of Radioanalytical and Nuclear Chemistry 2008, 276 (2), 467-473.

49.    Luo, S.; Greenfield, S.; Paisley, D.; Johnson, R.; Shimada, T.; Byler, D.; Loomis, E.; DiGiacomo, S.; Patterson, B.; McClellan, K. In Long pulse laser driven shock wave loading for dynamic materials experiments, High-Power Laser Ablation 2008, International Society for Optics and Photonics: 2008; pp 700514-700514-15.

50.    Patterson, B. M.; Havrilla, G. J.; Marcott, C.; Story, G. M., Infrared microspectroscopic imaging using a large radius germanium internal reflection element and a focal plane array detector. Applied Spectroscopy 2007, 61 (11), 1147-1152.

51.    Patterson, B. M.; Danielson, N. D.; Sommer, A. J., Polymer Mediated Capillary Electrophoresis with Attenuated Total Reflectance Infrared Microspectroscopy Detection. Analytica Chimica Acta 2007, 583 (2), 231-238.

52.    Labouriau, A.; Cox, J. D.; Schoonover, J. R.; Patterson, B. M.; Havrilla, G. J.; Stephens, T.; Taylor, D., Moessbauer, NMR and ATR-FTIR spectroscopic investigation of degradation in RTV siloxane foams. Polym. Degrad. Stab. 2007, 92 (3), 414-424.

53.    DeFriend, K. A.; Espinoza, B. F.; Patterson, B. M., Templating Silica Aerogel with Polystyrene to Improve Their Mechanical Properties. Fusion Sci. and Technol. 2007, 51 (4), 693-700.

54.    Patterson, B. M.; Havrilla, G. J.; Schoonover, J. R., Elemental and molecular characterization of aged polydimethylsiloxane foams. Appl. Spectrosc. 2006, 60 (10), 1103-1110.

55.    Patterson, B. M.; Havrilla, G. J., Integrating X-ray fluorescence and infrared imaging microspectroscopies for comprehensive characterization of an acetaminophen model pharmaceutical. Applied Spectroscopy 2006, 60 (5), 471-478.

56.    Patterson, B. M.; Havrilla, G. J., Attenuated total internal reflection infrared microspectroscopic imaging using a large-radius germanium internal reflection element and a linear array detector. Applied Spectroscopy 2006, 60 (11), 1256-1266.

57.    Patterson, B. M.; Danielson, N. D.; Sommer, A. J., Attenuated Total Internal Reflectance Infrared Microspectroscopy as a Detection Technique for Capillary Electrophoresis. Analytical Chemistry 2004, 76 (13), 3826-3832.

58.    Patterson, B. M.; Danielson, N. D.; Sommer, A. J., Attenuated total internal reflectance infrared microspectroscopy as a detection technique for high-performance liquid chromatography. Analytical Chemistry 2003, 75 (6), 1418-1424.

59.    Patterson, B. M.; Danielson, N. D.; Lorigan, G. A.; Sommer, A. J., Analytical Spectroscopy Using Modular Systems. J. Chem. Ed. 2003, 80 (12), 1460-1463.

60.    Lorigan, G. A.; Patterson, B. M.; Sommer, A. J.; Danielson, N. D., Cost-effective Spectroscopic Instrumentation for the Physical Chemistry Laboratory. J. Chem. Ed. 2002, 79 (10), 1264-1266.

Non-Peer Reviewed Publications:

61.    Cordes, N. L.; Henderson, K.; Stannard, T.; Williams, J. J.; Xiao, X.; Robinson, M.; Schaedler, T. A.; Chawla, N.; Patterson, B. M., 3D Imaging of Advanced Cellular Materials using in-situ Synchrotron-based X-ray Computed Tomography during Uniaxial Compression Loading. Microscopy Today 2015, 23 (3).

62.    Patterson, B. M.; Henderson, K.; Smith, Z.; Zhang, D.; Giguere, P., Application of Micro X-ray Tomography to In-situ Foam Compression and Numerical Modeling. Microscopy and Analysis 2012, 26 (2).

63.    Patterson, B. M., Staying on Target. Nuclear Weapons Journal 2009,  (1).

64.    Patterson, B. M.; Havrilla, G. J.; DeFriend, K. A., Confocal Micro X-ray Fluorescence: A New Paradigm in Materials Characterization. Microscopy Today 2008, 16 (4), 38-41.

65.    Bardenhagen S., G.; Patterson, B. M.; Cady, C. M.; Lewis Matthew, W.; Dattelbaum Dana, M., The Mechanics of LANL Foam Pads. ADTSC Nuclear Weapons Highlights 2007 2007, 07-041.

66.    Patterson, B. M.; Havrilla, G. J., Three-dimensional elemental imaging using a confocal x-ray fluorescence microscope. American Laboratory 2006, 38 (8), 15-16, 18, 21-22.