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LANL GFP Technology

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Green Fluorescent Protein (GFP) Toolbox protein graphic

Overview

Green Fluorescent Protein (GFP) has been around for many years and has been used in a lot of creative ways. Los Alamos National Laboratory researcher Dr. Geoff Waldo, has spent the last decade improving the flexibility, usability, reliability and sensitivity of GFP by engineering it to have more desirable characteristics. His work has resulted in a GFP that fluoresces more brightly, does not perturb the protein of interest, and works reliably in a number of important scientific applications. Not only does it perform better than other tags, but it is faster and cheaper!

To learn more about a particular application, read more details below:

Quantify the expression level of a target protein

Determine a target protein’s solubility

Discover which domains of a protein are soluble

Evaluate how a protein interacts with other proteins (protein-protein interaction)

Reveal the effect of a small molecule on the protein’s folding

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