Skip LANL navigation bars and bannerLos Alamos National LaboratoryGo to the Lab's home pageSearch for people in the Lab's directorySearch the Laboratory's Web site
Los Alamos National Laboratory Research Quarterly, Fall 2002
Stalking the AIDS Virus
Site Map News Jobs Maps Calendar Library Search
 
Dateline Los Alamos
Mesa View
RAPTOR Science
Stalking the Aids Virus
Nuclear Renaissance
Spotlight
 
  
 

HIV Subtypes

Bette Korber, postdoctoral research fellow John Mokili, and their Los Alamos colleagues have worked to clarify the evolutionary tree of HIV subtypes and strains. The evolutionary tree shows the genetic relationship among different viral strains, maps the genetic distance between several of the different subtypes of HIV (different colors), and indicates different strains within each subtype. By comparing the genomes (genetic information) of these viruses, Korber and others have been able to reconstruct a genome that would represent a consensus copy (arrow) of this genetic information. This genetic information can then be used to synthesize proteins that can, in turn, become the components of an AIDS vaccine. While at the Lab, Mokili has developed an HIV vaccine database, and he serves as advisor to vaccine developers in his native Democratic Republic of the Congo.

Bette Korber, postdoctoral research fellow John Mokili, and their Los Alamos colleagues have worked to clarify the evolutionary tree of HIV subtypes and strains. The evolutionary tree shows the genetic relationship among different viral strains, maps the genetic distance between several of the different subtypes of HIV (different colors), and indicates different strains within each subtype. By comparing the genomes (genetic information) of these viruses, Korber and others have been able to reconstruct a genome that would represent a consensus copy (arrow) of this genetic information. This genetic information can then be used to synthesize proteins that can, in turn, become the components of an AIDS vaccine. While at the Lab, Mokili has developed an HIV vaccine database, and he serves as advisor to vaccine developers in his native Democratic Republic of the Congo.

 

> return to Stalking the AIDS Virus

 

 

> return to Stalking the AIDS Virus

 
 Operated by the Los Alamos National Security, LLC for the U.S. Department of Energy's NNSA   
Inside
| © Copyright 2007-8 Los Alamos National Security, LLC All rights reserved | Disclaimer/Privacy
Web Contact