Los Alamos National Laboratory

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Evaluating the role of coherent delocalized phonon-like modes in DNA cyclization

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Evaluating the role of coherent delocalized phonon-like modes in DNA cyclization

The flexibility of the DNA molecule plays an important role in a multitude of biological functions as well as in the compact storage of the genetic material of cells. For example, the genome in each eukaryotic cell is tightly packed by sharply bending DNA around nucleosome and, similarly, DNA bending by transcription factors is a common cellular mechanism that participates in the regulation of gene expression. In the majority of cases, bending of DNA results in the formation of highly curved loops. (August 2017)

Summary of full paper (pdf)


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