LANL
A new computational and web-based tool called EDGE Bioinformatics is working to fulfill the promise of democratizing genomics.

Genomics for everyone

The research draws on Los Alamos’ expertise in computational modeling and health sciences and contributes to the Laboratory’s national security mission by protecting against biological threats. Infectious diseases are a leading cause of death globally.

Managing disease spread through accessible modeling

Cattle

On-the-range detection technology could corral bovine TB

Los Alamos research fundamental to first efficacy study for mosaic HIV-1 preventive vaccine

Los Alamos research fundamental to first efficacy study for mosaic HIV-1 preventive vaccine

The HIV-1 mosaic vaccine in the trial was originally designed at Los Alamos National Laboratory by theoretical biologist Bette Korber and her team. 30 Nov, 2017

30 Nov, 2017

Hunt is over for one of the ‘Top 50 Most-Wanted Fungi’

Hunt is over for one of the ‘Top 50 Most-Wanted Fungi’

Scientists have characterized a sample of “mystery” fungus collected in North Carolina and found its home in the fungal tree of life. 28 Sep, 2017

28 Sep, 2017

DNA detectives crack the case on biothreat look-alikes

DNA detectives crack the case on biothreat look-alikes

Biological “detectives” are tracking down biothreats such as the bacteria that causes tularemia (“rabbit fever”). 24 Aug, 2017

24 Aug, 2017

Genomic and fluid-flow technologies win regional tech-transfer awards

Genomic and fluid-flow technologies win regional tech-transfer awards

dfnWorks and EDGE Bioinformatics were recognized as “notable technology developments” by the consortium’s eight-member award review team. 10 Aug, 2017

10 Aug, 2017

Insight into enzyme’s 3D structure could cut biofuel costs

Insight into enzyme’s 3D structure could cut biofuel costs

Neutron crystallography maps LPMOs that break down fibrous cellulose 18 May, 2017

18 May, 2017

Managing disease spread through accessible modeling

Managing disease spread through accessible modeling

A new computer modeling study is aimed at making epidemiological models more accessible and useful for public-health collaborators and improving disease-related decision making. 25 Apr, 2017

25 Apr, 2017

Saturday Science with Geoff Fairchild

Saturday Science with Geoff Fairchild

Geoff Fairchild talk about how his team is using Los Alamos National Laboratory’s supercomputing capabilities to data mine social media and reveal trends relating to health and safety. 08 Apr, 2017

08 Apr, 2017

Los Alamos research on cancer’s origins key part of huge grant

Los Alamos research on cancer’s origins key part of huge grant

Ludmil Alexandrov has been announced as a member of one of the first four global research teams funded under Cancer Research UK’s “Grand Challenge." 09 Feb, 2017

09 Feb, 2017

Top Los Alamos science stories of 2016

Top Los Alamos science stories of 2016

From discoveries on Mars to breakthroughs in cancer research, from national security science to materials science, 2016 has proven to be another productive year for Los Alamos National Laboratory achievements. 21 Dec, 2016

21 Dec, 2016

DNA markers distinguish between harmless, deadly bacteria

DNA markers distinguish between harmless, deadly bacteria

The virulent pathogen that causes the disease tularemia, or “rabbit fever,” was weaponized during past world wars and is considered a potential bioweapon. 19 Dec, 2016

19 Dec, 2016

Bringing the power of genetic research to an office near you

Bringing the power of genetic research to an office near you

The ability to quickly analyze genetic data stands to revolutionize research into everything from the mutations causing various cancers to the “Second You,” your microbiome, or the bacteria living inside you. 10 Apr, 2016

10 Apr, 2016

Using Wikipedia to forecast the flu

Using Wikipedia to forecast the flu

Lab researchers use mathematics, computer science, statistics and other information to determine how disease develops and spreads. 15 Nov, 2016

15 Nov, 2016

Mutational signatures mark cancer's smoking gun

Mutational signatures mark cancer's smoking gun

A study of cancer genome sequences identifies telltale mutational signatures associated with smoking tobacco. 03 Nov, 2016

03 Nov, 2016

Los Alamos scientist recognized for work to increase availability of critical medical isotope

Los Alamos scientist recognized for work to increase availability of critical medical isotope

Iain May recognized for his work towards ensuring the reliability and domestic supply of a critical medical isotope used for diagnostic imaging. 20 Oct, 2016

20 Oct, 2016

Isotope research opens new possibilities for cancer treatment

Isotope research opens new possibilities for cancer treatment

The insights from this study could provide the needed chemical information to develop ways to bind actinium so that it can be safely transported through the body to the tumor cell. 17 Aug, 2016

17 Aug, 2016

Picture of the Week: Fighting the flu, one cell at a time

Picture of the Week: Fighting the flu, one cell at a time

To better understand autophagy in influenza A virus replication, a team of scientists from Los Alamos’ Biosecurity and Public Health group are taking a closer look at the role of Beclin-1, one of the key protein players in this intricate game of cellular life and death. 01 Aug, 2016

01 Aug, 2016

RNA simulations boost understanding of retroviral diseases

RNA simulations boost understanding of retroviral diseases

New molecular dynamics research into how RNA folds into hairpin-shaped structures called tetraloops could provide important insights into new treatments for retroviral diseases. 31 May, 2016

31 May, 2016

Physicist wins early-career award for isotope work

Physicist wins early-career award for isotope work

Jonathan Ward Engle, is among 49 winners, of the US Department of Energy’s Early Career Research Program awards for 2016. 12 May, 2016

12 May, 2016

Tiny plastic lung mimics human pulmonary function

Tiny plastic lung mimics human pulmonary function

Scientists are developing a miniature, tissue-engineered artificial lung that mimics the response of the human lung to drugs, toxins and other agents. 25 Apr, 2016

25 Apr, 2016

Bringing MRI where it’s needed most

Bringing MRI where it’s needed most

Los Alamos scientists developed a portable MRI, also called Battlefield MRI that uses ultra-low-field magnetic resonance imaging to create images of the brain that can be used in field hospitals for wounded soldiers or in remote villages in developing countries. 20 Mar, 2016

20 Mar, 2016

Science in 60 - The forecast calls for flu

Science in 60 - The forecast calls for flu

What if we could forecast infectious diseases the same way we forecast the weather, and predict how diseases like Dengue, Typhus or Zika were going to spread? 02 Mar, 2016

02 Mar, 2016

Analyzing genetic tree sheds new light on disease outbreaks

Analyzing genetic tree sheds new light on disease outbreaks

The team used computational phylogenetic analysis to examine how strains of HIV, both in computer modeling and compared with real-life case studies, would be transmitted. 25 Feb, 2016

25 Feb, 2016

Why is Zika now a threat?

Why is Zika now a threat?

Population growth, rising temperatures, embryonic immune systems says Lab scientist 25 Feb, 2016

25 Feb, 2016

Decoding dark matter in genes

Decoding dark matter in genes

Possible future applications, for example, include making new cancer therapies based on how ribosomes differentiate in healthy versus cancerous tissue. 19 Feb, 2016

19 Feb, 2016

Science on the Hill: The forecast calls for flu

Science on the Hill: The forecast calls for flu

Using mathematics, computer programs, statistics and information about how disease develops and spreads, a research team at Los Alamos National Laboratory found a way to forecast the flu season and even next week’s sickness trends. 15 Jan, 2016

15 Jan, 2016

Plasma research shows promise for future compact accelerators

Plasma research shows promise for future compact accelerators

A transformative breakthrough in controlling ion beams allows small-scale laser-plasma accelerators to deliver unprecedented power densities. 21 Dec, 2015

21 Dec, 2015

February most likely month for flu season to peak

February most likely month for flu season to peak

The Los Alamos team’s model is an ongoing research project that forecasts the current flu season probabilistically, similar to best-practice forecasts of weather, presidential elections, and sporting events. 20 Dec, 2015

20 Dec, 2015

Portable MRI named Top 10 Breakthrough of 2015 by Physics World magazine

Portable MRI named Top 10 Breakthrough of 2015 by Physics World magazine

Portable MRI, also called Battlefield MRI (bMRI), uses ultra-low-field magnetic resonance imaging to create images of injured soft tissues, such as the brain. 20 Dec, 2015

20 Dec, 2015

Los Alamos researcher pens prizewinning essay on cancer

Los Alamos researcher pens prizewinning essay on cancer

Ludmil Alexandrov made strong points this week in the journal Science winning a 2015 Science & SciLifeLab Prize, on “Understanding the Origins of Human Cancer.” 06 Dec, 2015

06 Dec, 2015

Molecular clocks control mutation rate in human cells

Molecular clocks control mutation rate in human cells

These clock-like mutational processes could ultimately be responsible for a large proportion of human cancer and contribute to human aging. 20 Nov, 2015

20 Nov, 2015

Novel targeted therapy for stomach cancer

Novel targeted therapy for stomach cancer

This finding has the potential to save thousand of lives a year by delivering a more effective, targeted treatment for cancer patients. 29 Oct, 2015

29 Oct, 2015

New insights into HIV-1 vaccine design

New insights into HIV-1 vaccine design

Scientists have created a computational model that could change the way that researchers look at possibilities for an HIV-1 vaccine. 17 Sep, 2015

17 Sep, 2015

Medical and biofuel advances possible with new gene regulation tool

Medical and biofuel advances possible with new gene regulation tool

The key is a tunable switch made from a small non-coding RNA molecule that could have value for medical and even biofuel production purposes. 20 Aug, 2015

20 Aug, 2015

Science on the Hill: Portable MRI might make the world a better place

Science on the Hill: Portable MRI might make the world a better place

Los Alamos' Battlefield MRI uses ultra-low-field magnetic resonance imaging to create images of the brain that can be used in field hospitals or in remote villages. 09 Aug, 2015

09 Aug, 2015

Project ATHENA creates surrogate human organ systems

Project ATHENA creates surrogate human organ systems

The development of miniature surrogate human organs, coupled with highly sensitive mass spectrometry technologies, could one day revolutionize the way new drugs and toxic agents are studied. 15 Jun, 2015

15 Jun, 2015

Science on the Hill: Rapid diagnosis a new weapon against re-emerging TB

Science on the Hill: Rapid diagnosis a new weapon against re-emerging TB

Researchers at Los Alamos National Laboratory have developed an innovative tool set for the early and accurate diagnosis of tuberculosis. 07 Jun, 2015

07 Jun, 2015

 Picture of the Week: Hot cells for medical isotopes

Picture of the Week: Hot cells for medical isotopes

Isotopes from Los Alamos are used for the diagnosis of cardiac disease, calibration of PET scanners which in turn diagnose cancer, neurological disease, inflammatory diseases, trauma, and other circulatory diseases, and are increasingly being investigated for their potential to treat a variety of localized pathologies. 07 Jun, 2015

07 Jun, 2015

DNA analysis conference in Santa Fe

DNA analysis conference in Santa Fe

Los Alamos National Laboratory is hosting a DNA sequence analysis and bioinformatics event, the 10th annual Sequencing, Finishing and Analysis in the Future (SFAF) workshop. 27 May, 2015

27 May, 2015

Using biomarkers to identify traumatic brain injury for soldiers, sports figures

Using biomarkers to identify traumatic brain injury for soldiers, sports figures

A new detection approach originally developed for tuberculosis diagnostics is being adapted as a tool for determining traumatic brain injury 28 Apr, 2015

28 Apr, 2015

Portable MRI could aid wounded soldiers and children in the Third World

Portable MRI could aid wounded soldiers and children in the Third World

Scientists are developing a low power, lightweight, ultra-low-field MRI system for battlefield deployment and field hospitals in the world's poorest regions 22 Apr, 2015

22 Apr, 2015

Los Alamos creates bioinformatics tool for metagenome analysis

Los Alamos creates bioinformatics tool for metagenome analysis

Scientists have developed a new method for DNA analysis of microbial communities such as those found in the ocean, the soil, and our own guts. 18 Mar, 2015

18 Mar, 2015

Scientists call for antibody 'bar code’ system to follow Human Genome Project

Scientists call for antibody 'bar code’ system to follow Human Genome Project

Researchers have collaborated to craft a request that could fundamentally alter how the antibodies used in research are identified. 04 Feb, 2015

04 Feb, 2015

Supporting biosurveillance via the web

Supporting biosurveillance via the web

A new online resource is providing a centralized portal for all news, information, resources and research related to biosurveillance at the Laboratory. 28 Jan, 2015

28 Jan, 2015