News
Prevention and management of oral diseases may get a boost
October 28, 2010—LANL scientists—Gary Xie, Patrick Chain, Chien-Chi Lo, and Kuan-Liang Liu of Genome Science/Joint Genome Institute (B-6) and Jason Gans of Biosecurity and Public Health (B-7)—along with collaborators from the University of Oklahoma have completed the first gene catalog of the community of microorganisms in human healthy dental plaque.
Their findings support the plaque hypothesis for oral diseases, which suggests that changes in the environment of an individual's mouth are the determining factors as to whether one gets periodontal disease. For example, a simple change in an individual's pH or a decrease in the amount of saliva could lead to a large alteration of the microbial composition of a plaque. The researchers obtained the first glimpse of the genomic contents of a community of microscopic organisms that live within human plaque.
Fast Facts
People
11,127 total employees
Los Alamos National Security, LLC 8,683
SOC Los Alamos (Guard Force) 419
Contractors 606
Students 1,101
Place
Located 35 miles northwest of Santa Fe, New Mexico, on 36 square miles of DOE-owned property.
More than 2,000 individual facilities, including 47 technical areas with 8 million square feet under roof.
Replacement value of $5.9 billion
Budget FY 2012: Approx. $2.2 billion
57% Weapons programs
9% Nonproliferation programs
7% Safeguards and Security
8% Environmental Management
4% DOE Office of Science
4% Energy and other programs
11% Work for Others
Workforce Demographics (LANS and students only)
34% of employees live in Los Alamos, the remainder commute from Santa Fe,
Española, Taos, and Albuquerque.
Average Age: 46
70% male, 30% female
43% minorities
63% university degrees
· 23% hold undergraduate degrees
· 16% hold graduate degrees
· 24% have earned a Ph.D.
Major Awards
121 R&D100 awards since 1978
31 E.O. Lawrence Awards
The Seaborg Medal
The Edward Teller Medal
The Nobel Prize in Physics, Frederick Reines

