Center for Integrated Nanotechnologies

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Jennifer Martinez

Jen Martinez

Phone (505) 665-0045


  • CINT
  • Synthesis
  • Manipulate/Assemble


Soft, Biological and Composite Nanomaterials


Ph.D., Chemistry, University of California, 2002

B.S., Chemistry, University of Utah, 1994


Professional Appointments

Technical Staff Member, Center for Integrated Nanotechnologies 2005 - Present

Technical Staff Member, Bioscience Division 2004 - 2005

Directors Funded Postdoctoral Fellow, Bioscience Division 2002 - 2004



Presidential Early Career Award for Science and Engineering, 2008

LANL Outstanding Mentoring Award, 2007

Directors Postdoctoral Fellow, LANL, 2002

B.R. Baker Award, Outstanding Chemistry, UCSB

California SeaGrant Traineeship, UCSB

Graduate Opportunity Fellow, UCSB

Entrepreneurial Scholarship, JA, University of Utah



Fluorescence-enhancement of DNA-silver nanoclusters from guanine proximity. H.-C, Yeh, J.
Sharma, J.S. Martinez, J.H. Werner S-18,917, 2010

Synthesis of fluorescent metal nanoclusters. J.S. Martinez, R. B. Dyer, D. M. Vu, C. Zhong, Y. Bao.
Nonprovisional Patent Application number: 11/786,190, 2007

Planar optical waveguide based sandwich assay sensors and processes for the detection of biological
targets including early detection of cancers. Martinez, J.S., Swanson, B.I., Shively, J.E. Li, L. U.S.
Patent 7,541,196 (2009)

Planar optical waveguide based sandwich assay sensors and processes for the detection of biological
targets including protein markers, pathogens and cellular debris. Martinez, J.S., Swanson, B.I.,
Grace, K.M., Grace, W.K., Shreve, A.P. U.S. Patent 7,541,197 (2009)

Modulated Optical Waveguide-Sensor, B.I. Swanson, J.G. Schmidt, J.S. Martinez, A. A. Anderson,
Patent Application, 60/649,753, 2005, provisional.

Waveguide-Based Sensors for the Early Detection of Cancer, B. I. Swanson, J.S. Martinez, K. M.
Grace, W. K. Grace, J. Shively, L. Lee, Provisional 60/583911, Application S-103,367, 7/2005.



[Bao, YP * Zhong, C * Vu, DM * Temirov, JP * Dyer, RB * Martinez, JS], "Nanoparticle-free synthesis of fluorescent gold nanoclusters at physiological temperature", JOURNAL OF PHYSICAL CHEMISTRY C, Vol.111, iss.33, p.12194-12198, AUG 23 2007.

[Zhong, C * Bao, YP * Vu, DM * Dyer, RB * Martinez, JS], "Fabrication of fluorescent cellular probes: Hybrid dendrimer/gold nanoclusters", Materials Research Society Symposium Proceedings, Vol.1007, p.265-270, 2008.

[Rebecca, M * Hsing-Lin, W * Jun, G * Srinivas, I * Gabriel, MA * Jennifer, M * Andrew, SP * Bao, YP * Chun-Chih, W * Zhong, C * Yuan, G * Rashi, I], "Impact of physicochemical properties of engineered fullerenes on key biological responses", TOXICOLOGY AND APPLIED PHARMACOLOGY, Vol.234, iss.1, p.58-67, JAN 1 2009.

[Mukundan, H. * Hongzhi Xie * Anderson, A. * Grace, W.K. * Martinez, J.S. * Swanson, B.], "Toward photostable multiplex analyte detection on a single mode planar optical waveguide", Proceedings of the SPIE - The International Society for Optical Engineering, vol.7167, p.71670A, 2009.

[Mukundan, H. * Kubicek, J.Z. * Holt, A. * Shively, J.E. * Martinez, J.S. * Grace, K. * Grace, W.K. * Swanson, B.I.], "Planar optical waveguide-based biosensor for the quantitative detection of tumor markers", Sensors and Actuators, B: Chemical, Vol.138, iss.2, p.453-460, 20090506.

[Mukundan, H * Anderson, AS * Grace, WK * Grace, KM * Hartman, N * Martinez, JS * Swanson, BI], "Waveguide-Based Biosensors for Pathogen Detection", SENSORS, Vol.9, iss.7, p.5783-5809, JUL 2009.

[Mukundan, H * Xie, HZ * Price, D * Kubicek-Sutherland, JZ * Grace, WK * Anderson, AS * Martinez, JS * Hartman, N * Swanson, BI], "Quantitative Multiplex Detection of Pathogen Biomarkers on Multichannel Waveguides", ANALYTICAL CHEMISTRY, Vol.82, iss.1, p.136-144, JAN 1 2010.

[Belyea, JL * Zhong, C * Bao, YP * Martinez, JS * Dyer, RB * Vu, DM], "INOR 601-Gold fluorescent nanocluster synthesis within a protein scaffold", ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol.236, AUG 17 2008.

[Sharma, J * Yeh, HC * Yoo, H * Werner, JH * Martinez, JS], "A complementary palette of fluorescent silver nanoclusters", CHEMICAL COMMUNICATIONS, Vol.46, iss.19, p.3280-3282, 2010.

[Hsin-Chih Yeh * Sharma, J. * Hyojong Yoo * Martinez, J.S. * Werner, J.H.], "Photophysical characterization of fluorescent metal nanoclusters synthesized using oligonucleotides, proteins and small molecule ligands", Proceedings of the SPIE - The International Society for Optical Engineering, vol.7576, p.75760N, 2010.

[Yeh, HC * Sharma, J * Han, JJ * Martinez, JS * Werner, JH], "A DNA-Silver Nanocluster Probe That Fluoresces upon Hybridization", NANO LETTERS, Vol.10, iss.8, p.3106-3110, AUG 2010.

[Yoo, H * Sharma, J * Yeh, HC * Martinez, JS], "Solution-phase synthesis of Au fibers using rod-shaped micelles as shape directing agents", CHEMICAL COMMUNICATIONS, Vol.46, iss.36, p.6813-6815, 2010.

[Bao, YP * Yeh, HC * Zhong, C * Ivanov, SA * Sharma, JK * Neidig, ML * Vu, DM * Shreve, AP * Dyer, RB * Werner, JH * Martinez, JS], "Formation and Stabilization of Fluorescent Gold Nanoclusters Using Small Molecules", JOURNAL OF PHYSICAL CHEMISTRY C, Vol.114, iss.38, p.15879-15882, SEP 30 2010.

[Bock, J * Fukuyo, Y * Kang, S * Phipps, ML * Alexandrov, LB * Rasmussen, KO * Bishop, AR * Rosen, ED * Martinez, JS * Chen, HT * Rodriguez, G * Alexandrov, BS * Usheva, A], "Mammalian Stem Cells Reprogramming in Response to Terahertz Radiation", PLOS ONE, Vol.5, iss.12, e15806, DEC 31 2010.

[Sharma, J * Yeh, HC * Yoo, H * Werner, JH * Martinez, JS], "Silver nanocluster aptamers: in situ generation of intrinsically fluorescent recognition ligands for protein detection", CHEMICAL COMMUNICATIONS, Vol.47, iss.8, p.2294-2296, 2011.

[Martin, Jennifer S.], "Synthesis and assembly of nanoarchitectures: Fluorescent nanoclusters", Abstracts of Papers American Chemical Society, Vol.238, p.216-PHYS, AUG 16 2009.

[Neidig, M.L. * Sharma, J. * Yeh, H.-C. * Martinez, J.S. * Conradson, S.D. * Shreve, A.P.], "Ag K-edge EXAFS analysis of DNA-templated fluorescent silver nanoclusters: Insight into the structural origins of emission tuning by DNA sequence variations", Journal of the American Chemical Society, Vol.133, iss.31, p.11837-11839, 20110810.

[Sharma, JK * Yeh, HC * Werner, JH * Martinez, JS], "Synthesis of oligonucleotide-templated fluorescent silver-nanoclusters with enhanced photochemical stability", ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol.241, MAR 27 2011.

[Yeh, HC * Sharma, JK * Han, JJ * Martinez, JS * Werner, JH], "Nano Cluster Beacon (NCB): A DNA-silver nanocluster probe that fluoresces upon hybridization", ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol.241, MAR 27 2011.

[Hsin-Chih Yeh * Sharma, J. * Han, J.J. * Martinez, J.S. * Werner, J.H.], "NanoCluster Beacon - A New Molecular Probe for Homogeneous Detection of Nucleic Acid Targets", Proceedings of the 2011 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS 2011), p.267-70, 2011.

[Yeh, H.-C. * Sharma, J. * Han, J.J. * Martinez, J.S. * Werner, J.H.], "A beacon of light: A new molecular probe for homogeneous detection of nucleic acid targets", IEEE Nanotechnology Magazine, Vol.5, iss.2, p.28-33, June 2011.

[Yoo, H * Sharma, J * Kim, JK * Shreve, AP * Martinez, JS], "Tailored Microcrystal Growth: A Facile Solution-Phase Synthesis of Gold Rings", ADVANCED MATERIALS, Vol.23, iss.38, p.4431-+, OCT 11 2011.

[Martinez, JS * Werner, JH * Yeh, HC * Sharma, J * Shreve, AP * Neidig, ML * Ivanov, S * Arachchige, I], "Characterization and application of small-molecule- and DNA-templated gold and silver fluorescent nanoclusters", ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol.242, AUG 28 2011.

[Alexandrov, BS * Rasmussen, KO * Bishop, AR * Usheva, A * Alexandrov, LB * Chong, S * Dagon, Y * Booshehri, LG * Mielke, CH * Phipps, ML * Martinez, JS * Chen, HT * Rodriguez, G], "Non-thermal effects of terahertz radiation on gene expression in mouse stem cells", BIOMEDICAL OPTICS EXPRESS, Vol.2, iss.9, p.2679-2689, SEP 1 2011.

[Cannon, WR * Talley, ND * Danzig, BA * Liu, XM * Martinez, JS * Shreve, AP * MacDonald, G], "Ion specific influences on the stability and unfolding transitions of a naturally aggregating protein; RecA", BIOPHYSICAL CHEMISTRY, Vol.163, p.56-63, APR 2012.

[Yau, SH * Abeyasinghe, N * Orr, M * Upton, L * Varnavski, O * Werner, JH * Yeh, HC * Sharma, J * Shreve, AP * Martinez, JS * Goodson, T], "Bright two-photon emission and ultra-fast relaxation dynamics in a DNA-templated nanocluster investigated by ultra-fast spectroscopy", NANOSCALE, Vol.4, iss.14, p.4247-4254, 2012.

[Sharma, J * Rocha, RC * Phipps, ML * Yeh, HC * Balatsky, KA * Vu, DM * Shreve, AP * Werner, JH * Martinez, JS], "A DNA-templated fluorescent silver nanocluster with enhanced stability", NANOSCALE, Vol.4, iss.14, p.4107-4110, 2012.

[Yeh, HC * Sharma, J * Shih, IM * Vu, DM * Martinez, JS * Werner, JH], "A Fluorescence Light-Up Ag Nanocluster Probe That Discriminates Single-Nucleotide Variants by Emission Color", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol.134, iss.28, p.11550-11558, JUL 18 2012.

[Alexandrov, Boian S. * Phipps, M. Lisa * Alexandrov, Ludmil B. * Booshehri, Layla G. * Erat, Anna * Zabolotny, Janice * Mielke, Charles H. * Chen, Hou-Tong * Rodriguez, George * Rasmussen, Kim O. * Martinez, Jennifer S. * Bishop, Alan R. * Usheva, Anny], "Specificity and Heterogeneity of Terahertz Radiation Effect on Gene Expression in Mouse Mesenchymal Stem Cells", SCIENTIFIC REPORTS, Vol.3, p.1184, JAN 31 2013.

[Werner, James * Martinez, Jennifer S. * Sharma, Jaswinder K. * Yeh, Hsin-Chih], "DNA-Templated Silver Nanoclusters that Fluoresce upon Hybridization", BIOPHYSICAL JOURNAL, Vol.104, iss.2, suppl.1, p.545A-545A, JAN 29 2013.

[Park, Young Il * Zhang, Bingqi * Kuo, Cheng-Yu * Martinez, Jennifer S. * Park, Jongwook * Mallapragada, Surya * Wang, Hsing-Lin], "Stimuli-Responsive Poly-N-isopropylacrylarnide: Phenylene Vinylene Oligomer Conjugate", JOURNAL OF PHYSICAL CHEMISTRY C, Vol.117, iss.15, p.7757-7763, APR 18 2013.

[Park, Young Il * Kuo, Cheng-Yu * Martinez, Jennifer S. * Park, Young-Shin * Postupna, Olena * Zhugayevych, Andriy * Kim, Seungho * Park, Jongwook * Tretiak, Sergei * Wang, Hsing-Lin], "Tailored electronic structure and optical properties of conjugated systems through aggregates and dipole-dipole interactions", ACS Applied Materials and Interfaces, Vol.5, iss.11, p.4685-4695, 2013.