Center for Integrated Nanotechnologies

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James Henry Werner

Jim Werner

Phone (505) 667-8842


  • Biosciences
  • Single cell genomics
  • Biomaterials
  • Optical imaging and tomography of biological tissue
  • Materials
  • Microfabrication
  • Nanotechnology
  • Optics and fiber optics
  • Nanoscale (in time and space) spectroscopies
  • Biological assemblies
  • Center for Integrated Nanotechnologies (CINT)
  • CINT
  • Structure Measurements
  • Property Measurements
  • Function/Response Measurements
  • Characterization





Instrument Development


B.S., Applied Physics, California Institute of Technology, 1992

M.S., Applied Physics, Cornell University, 1994

Ph.D., Applied Physics, Cornell University, 1998


Professional Appointments

Technical Staff Member, 2002 - present

Postdoctoral Research Associate, 1998 - 2002


Professional Societies

Biophysical Society

American Chemical Society

American Physical Society



Fellow, American Physical Society, 2016

Los Alamos Distinguished Patent Award, 2011

R&D 100 Award “NanoCluster Beacons” , 2011

Los Alamos Postdoctoral Distinguished Mentor Award, 2011

R&D 100 Award “3D Tracking Microscope” (2008)

Hertz Foundation Fellowship (1992-1997)




"Apparatus and method for tracking a molecule or particle in three dimensions," Werner, JH, Goodwin PM, and Lessard GA, US Patent 7,498,551 (2009).

3 Dimensional Imaging at Nanometer Resolutions," Werner, JH, Goodwin, PM and Shreve, AP, US Patent 7,675,045, (2010).

"Probe and Method for DNA Detection," Yeh, HC, Sharma, JK, Martinez, JS and Werner, JH, US Patent Application No. 20110212540, (2011).





"Multicolor Three-Dimensional Tracking for Single-Molecule Fluorescence Resonance Energy Transfer Measurements," A. M. Keller, M.S. DeVore, D. G. Stich, D. M. Vu,T. Causgrove, and James H. Werner, Analytical Chemistry 90, 6109−6115 (2018).

"Light-sheet microscopy by confocal line scanning of dual-Bessel beams," Zhang, P., Phipps, ME, Goodwin, P, and Werner, J., Journal of Biomedical Optics 21(10), 100502 (2016).

"Note: Time-gated 3D single quantum dot tracking with simultaneous spinning disk imaging," DeVore, M, Stich, D, Keller, A, Cleyrat, C, Phipps, M, Hollingsworth, J, Lidke, D, Wilson, B, Goodwin, P and Werner, J, Review of Scientific Instruments 86, 126102, (2015).

"Interferometric three-dimensional single molecule localization microscopy using a single high-numerical-aperture objective," Zhang, P, Goodwin, P and Werner, J, Applied Optics 53, 7415-7421, (2014).

"3Dimensional Tracking of Nonblinking ‘Giant’Quantum Dots in Live Cells," Keller, AM, Ghosh, Y, DeVore, MS, Phipps, ME, Stewart, MH, Wilson, BS, Lidke, DS, Hollingsworth, JA and Werner, JH, Advanced Functional Materials 24, 4796-4803, (2014).

"Fast, super resolution imaging via Bessel-beam stimulated emission depletion microscopy," Zhang, P, Goodwin, P and Werner, J, Optics Express 22, 12398-12409, (2014).