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Christine Michaela Anderson-Cook

Christine Anderson-Cook

Phone (505) 606-0347


  • Computational Physics and Applied Mathematics
  • Statistics
  • Information Science and Technology
  • Uncertainty quantification (UQ)
  • Latin hypercube sampling (LHS)
  • Visualization


Design of experiments

Response surface methodology

Decision-making for multiple objectives

System reliability


Ph.D. Statistics, University of Waterloo, 1994

M.S. Statistics, University of Toronto, 1990

B. Math, University of Waterloo, 1989

B. Education, University of Western Ontario, 1989


LANL Positions

Project Leader, Complex System Health Assessment - October 2009 to present

Project Leader, Munitions Stockpile Reliability Assessment - September 2006 to Sept 2010

Research Scientist 4  - July 2008 to present

Technical Staff Member  - June 2004 to July 2008


Professional Societies

Fellow of the American Statistical Association (2006) and the American Society for Quality (2011)



Recipient of the ASQ Statistics Division William G. Hunter Award, 2012. The “award recognizes that person whose actions most closely mirror Bill Hunter’s strengths as a communicator, consultant, educator (especially for practitioners), innovator, integrator (of statistics with other disciplines) and implementer (who obtained results).”

Recipient (with Lu Lu and Timothy Robinson) of the ASQ Chemical and Process Industries Division Shewell Award for best paper based on “excellence of presentation and written manuscript” at the 2011 Fall Technical Conference

Recipient of Los Alamos National Laboratory Postdoc Distinguished Mentor Award, 2011

Recipient of 26th Annual Governor’s Award for Outstanding New Mexico Women, 2011 for “community leadership, advocacy on behalf of others, or trailblazers in their professions. They are recognized for their extraordinary contributions in empowering the status of women in the state.”

Department of Energy Defense Programs Award of Excellence for significant contributions to the Stockpile Stewardship Program through contributions to the Joint Munitions Program, 2009

Led Los Alamos portion of the Joint Project between the Department of Statistics at Iowa State University and the Statistical Sciences Group at Los Alamos National Laboratory, which was selected as the 2009 American Statistical Association SPAIG (Statistical Partnerships among Academe, Industry and Government) Award recipient (Award recognizes outstanding partnerships established between academe and business, industry, & government organizations)

Los Alamos National Laboratory STAR award, 2009 (Award in recognition of those who go above and beyond the call of duty in the performance of their job functions, women who have achieved scientific or technical success, and women who make important contributions to the community)

Selected to give the Youden Address at the 2008 Fall Technical Conference in Phoenix, AZ. (The Youden address speaker is chosen based on being “a recognized leader in the development or application of statistical methodologies, extensively promote statistics and the statistical applications to everyday problems, being well published, and being a vibrant and passionate speaker.”)

Best Paper in the Propulsion Session at the American Helicopter Society conference, 2001 for “Analysis Methods To Control Performance Variability and Costs in Airplane Turbine Engine Manufacturing” with Karl Sheldon and W.F. O’Brien.

Best Contributed Paper from the Section of Statistical Education at the Joint Statistical Meetings, 2000 for “A Teaching Exercise for the Basic Concepts of Experimental Design” with Sundar Dorai-Raj.



Myers, R.H., Montgomery, D.C., Anderson-Cook, C.M. (2009). Response Surface Methodology: Process and Product Optimization Using Designed Experiments. 3rd Ed. New York: Wiley.

Refereed Journal Articles (selected from over 100 peer-reviewed papers):

Chapman, J.L., Lu, L., Anderson-Cook, C.M. (2014) “Incorporating Response Variability and Estimation Uncertainty into Pareto Front Optimization” Computers & Industrial Engineering 76 253-267

Lu, L., Johnson, M.E., Anderson-Cook, C.M., (2014) “Selecting a Best Two Level 16-run Screening Design from the Catalog of Non-Isomorphic Regular and Non-Regular Designs for Six to Eight Factors” Quality Engineering, Vol 26 269–284.

Chapman, J., Lu, L., Anderson-Cook, C.M. (2014) “Process Optimization for Multiple Responses Utilizing the Pareto Front Approach” Quality Engineering, Vol 26 253–268.

Lu, L., Chapman, J., Anderson-Cook, C.M. (2013) “A Case Study on Selecting A Best Allocation of New Data for Improving the Estimation Precision of System and Sub‐System Reliability using Pareto Fronts” Technometrics, Vol 55 473-487

Anderson-Cook, C.M. & Borror, C.M. (2013) “Paving the Way: Seven Data Collection Strategies to Enhance your Quality Analyses” Quality Progress, Vol 46 (4), 18-29.

Chapman, J., Morris, M., Anderson-Cook, C.M. (2012) “Computationally Efficient Comparison of Experimental Designs for System Reliability Studies with Binomial Data” Technometrics 54 410-424.

Robinson, T.J., Pintar, A., Anderson-Cook, C.M., Hamada, M.S. (2012) “A Bayesian Approach to the Analysis of Split-Plot Product Arrays and Optimization in Robust Parameter Design” Journal of Quality Technology 44 304-320.

Pintar, A., Lu, L., Anderson-Cook, C.M., Silver, G.L. (2012) “Bayesian Estimation of Reliability for Batches of High Reliability Single-Use Parts” Quality Engineering 24 473-485.

Lu L., Anderson-Cook, C.M. (2012) “Rethinking the Optimal Response Surface Design for a First-Order Model with Two-Factor Interactions, when Protecting against Curvature" Quality Engineering 24 404-422.

Lu, L., Anderson-Cook, C.M., Robinson, T.J. (2012) “A Case Study to Demonstrate Pareto Frontiers for Selecting a Best Response Surface Design with Simultaneously Optimizing Multiple Criteria” Applied Stochastic Models in Business and Industry 28 206-221.

Anderson-Cook, C.M., Klamann, R.M., Morzinski, J. (2012) “Modeling the Reliability of Complex Systems with Multiple Data Sources: A Case Study on Making Statistical Tools Accessible to Engineers” Quality Engineering 24 280-291.

Anderson-Cook, C.M., Lu, L., Clark, G., DeHart, S.P., Hoerl, R., Jones, B., MacKay, R.J., Montgomery, D.C., Parker, P.A., Simpson, J., Snee, R., Steiner, S., Van Mullekom, J., Vining, G.G., Wilson, A.G.  (2012) “Statistical Engineering – Roles for Statisticians and the Path Forward” Quality Engineering 24 133-152.

Anderson-Cook, C.M., Lu, L., Clark, G., DeHart, S.P., Hoerl, R., Jones, B., MacKay, R.J., Montgomery, D.C., Parker, P.A., Simpson, J., Snee, R., Steiner, S., Van Mullekom, J., Vining, G.G., Wilson, A.G.  (2012) “Statistical Engineering – Forming the Foundations” Quality Engineering 24 110-132.

Jensen, W., Anderson-Cook, C.M., Costello, J., Doganaksoy, N., Dorai-Raj, S., Hoerl, R., Janis, S., O’Neill, J., Rodebaugh, W., Snee, R. (2012) “Statistics to Facilitate Innovation: A Panel Discussion” Quality Engineering 24 2-19.

Lu, L., Anderson-Cook, C.M., Robinson, T.J. (2011) “Optimization of Designed Experiments Based on Multiple Criteria Utilizing a Pareto Frontier” Technometrics 53 353-365.Wilson, A.G., Anderson-Cook, C.M., Huzurbazar, A.V. (2011) “A Case Study for Quantifying System Reliability and Uncertainty” Reliability Engineering & System Safety 1076-1084.

Anderson-Cook, C.M., Crowder, S., Huzurbazar, A.V., Lorio, J., Ringland, J., Wilson, A.G. (2011) “Quantifying Reliability Uncertainty from Catastrophic and Margin Defects: A Proof of Concept” Reliability Engineering & System Safety 1063-1075.

Izraelevitz, A., Anderson-Cook, C.M., Hamada, M.S. (2011) “Illustrating the Use of Statistical Experimental Design and Analysis for Multiresponse Prediction and Optimization” Quality Engineering 23 265-277.

Collins, D.H., Anderson-Cook, C.M., Huzurbazar, A.V. (2011) "System Health Assessment" Quality Engineering 23 142-151.

Lu, L., Anderson-Cook, C.M. (2011) “Using Age and Usage for Prediction of Reliability of an Arbitrary System from a Finite Population” Quality and Reliability Engineering International 27 179-190.

Graves, T.L., Anderson-Cook, C.M., Hamada, M.S. (2010) “Reliability Models for Almost-Series and Almost-Parallel Systems” Technometrics 52 160-171.

Monroe, E.M., Pan, R., Anderson-Cook, C.M., Montgomery, D.C., Borror, C.M. (2010) “Sensitivity Analysis of Optimal Designs for Accelerated Life Testing” Journal of Quality Technology 42 121-135.

Anderson-Cook, C.M., Borror, C.M., Jones, B. (2009) “Graphical Tools for Assessing the Sensitivity of Response Surface Designs to Model Misspecification”Technometrics 51 75-87.

Robinson, T.J., Anderson-Cook, C.M., Hamada, M. (2009) “Bayesian Analysis of Split-Plot Experiments with Non-Normal Responses for Evaluating Non-Standard Performance Criteria” Technometrics 51 56-65.

Anderson-Cook, C.M., Borror, C.M., Montgomery, D.C. (2009) “Response Surface Design Evaluation and Comparison” (with discussion and rejoinder) Journal of Statistical Planning and Inference 139 629-641, 671-674.

Zahran, A., Anderson-Cook, C.M. and Myers, R.H. (2003) “Fraction of Design Space to Assess the Prediction Capability of Response Surface Designs”. Journal of Quality Technology 35 377-386.