Los Alamos National Laboratory

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Christine Michaela Anderson-Cook

Christine Anderson-Cook

Phone (505) 606-0347


  • Computational Physics and Applied Mathematics
  • Statistics
  • Uncertainty quantification
  • Uncertainty analysis
  • Computer and Computational Sciences
  • High performance computing
  • Information Science and Technology
  • Uncertainty quantification (UQ)
  • Latin hypercube sampling (LHS)
  • Visualization
  • Cybersecurity


Design of experiments

Response surface methodology

Decision-making for multiple objectives

System reliability

Graphical methods


Ph.D. Statistics, University of Waterloo, 1994

M.S. Statistics, University of Toronto, 1990

B. Math, University of Waterloo, 1989

B. Education, University of Western Ontario, 1989


LANL Positions

Project Leader, National Technical Nuclear Forensics Center "Statistical Support for Design & Analysis for Nuclear Forensics" (2014-present)

Project Leader, Joint Munitions Program "Complex System Health Assessment" (2009-2016)

Research Scientist 4 (2008-present)

Technical Staff Member (2004-2008)


Professional Societies

Fellow of the American Statistical Association (2006) and the American Society for Quality (2011)



ASQ Statistics Division William G. Hunter Award, 2012. The “award recognizes that person whose actions most closely mirror Bill Hunter’s strengths as a communicator, consultant, educator (especially for practitioners), innovator, integrator (of statistics with other disciplines) and implementer (who obtained results).”

Conference Honoree at 2016 Quality and Productivity Research Conference

LANL Student Distinguished Mentor Award, 2015

LANL Postdoc Distinguished Mentor Award, 2011

LANL STAR award, 2009

26th Annual Governor’s Award for Outstanding New Mexico Women, 2011 for “community leadership, advocacy on behalf of others, or trailblazers in their professions. They are recognized for their extraordinary contributions in empowering the status of women in the state.”

Department of Energy Defense Programs Award of Excellence for significant contributions to the Stockpile Stewardship Program through contributions to the Joint Munitions Program, 2009



Myers, R.H., Montgomery, D.C., Anderson-Cook, C.M. (2016, 2009). Response Surface Methodology: Process and Product Optimization Using Designed Experiments. 4th and 3rd Eds. New York: Wiley.

Anderson-Cook, C.M., Lu, L. (2016). Statistical Roundtables: Insights and Best Practices. Milwaukee: ASQ Press.

Refereed Journal Articles (selected from over 150 peer-reviewed papers):

Anderson-Cook, C.M., Hamada, M.S., Moore, L.M., Wendelberger, J.R. (2017) “Statistical Mentoring at Early Training and Career Stages” The American Statistician 71 6-14.

Anderson-Cook, C.M. (2017) “Optimizing in a Complex World: Statisticians’ Roles in Decision-Making” (with discussion and rejoinder) Quality Engineering 29 (1) 27-41, 54-56.

Lu, L., Li, M., Anderson-Cook, C.M. (2016) “Multiple Objective Optimization in Reliability Demonstration Testing” Journal of Quality Technology 48 (4) 326-342.

Weaver, B.P., Williams, B.J., Anderson-Cook, C.M., Higdon, D.M. (2016) “Computational Enhancements to Bayesian Design of Experiments using Gaussian Processes” Bayesian Analysis 11 191-213.

Anderson-Cook, C.M., Burr, T., Hamada, M.S., Ruggiero, C., Thomas, E.V. (2015) “Design of Experiments and Data Analysis Challenges in Calibration for Forensics Applications” Chemometrics and Intelligent Laboratory Systems 149(B) 107-117.

Anderson-Cook, C.M. (2015) “Opportunities to Empower Statisticians in Emerging Areas” (with discussion and rejoinder) Applied Stochastic Models in Business and Industry 31 3-11 & 15.

Chapman, J.L., Lu, L., Anderson-Cook, C.M. (2014) “Incorporating Response Variability and Estimation Uncertainty into Pareto Front Optimization” Computers & Industrial Engineering 76 253-267.

Lu, L., Johnson, M.E., Anderson-Cook, C.M., (2014) “Selecting a Best Two Level 16-run Screening Design from the Catalog of Non-Isomorphic Regular and Non-Regular Designs for Six to Eight Factors” Quality Engineering, Vol 26 269–284.

Anderson-Cook, C.M. & Borror, C.M. (2013) “Paving the Way: Seven Data Collection Strategies to Enhance your Quality Analyses” Quality Progress, Vol 46 (4), 18-29.

Chapman, J., Morris, M., Anderson-Cook, C.M. (2012) “Computationally Efficient Comparison of Experimental Designs for System Reliability Studies with Binomial Data” Technometrics 54 410-424.

Robinson, T.J., Pintar, A., Anderson-Cook, C.M., Hamada, M.S. (2012) “A Bayesian Approach to the Analysis of Split-Plot Product Arrays and Optimization in Robust Parameter Design” Journal of Quality Technology 44 304-320.

Pintar, A., Lu, L., Anderson-Cook, C.M., Silver, G.L. (2012) “Bayesian Estimation of Reliability for Batches of High Reliability Single-Use Parts” Quality Engineering 24 473-485.

Lu L., Anderson-Cook, C.M. (2012) “Rethinking the Optimal Response Surface Design for a First-Order Model with Two-Factor Interactions, when Protecting against Curvature" Quality Engineering 24 404-422.

Anderson-Cook, C.M., Klamann, R.M., Morzinski, J. (2012) “Modeling the Reliability of Complex Systems with Multiple Data Sources: A Case Study on Making Statistical Tools Accessible to Engineers” Quality Engineering 24 280-291.

Anderson-Cook, C.M., Lu, L., Clark, G., DeHart, S.P., Hoerl, R., Jones, B., MacKay, R.J., Montgomery, D.C., Parker, P.A., Simpson, J., Snee, R., Steiner, S., Van Mullekom, J., Vining, G.G., Wilson, A.G.  (2012) “Statistical Engineering – Roles for Statisticians and the Path Forward” Quality Engineering 24 133-152.

Anderson-Cook, C.M., Lu, L., Clark, G., DeHart, S.P., Hoerl, R., Jones, B., MacKay, R.J., Montgomery, D.C., Parker, P.A., Simpson, J., Snee, R., Steiner, S., Van Mullekom, J., Vining, G.G., Wilson, A.G.  (2012) “Statistical Engineering – Forming the Foundations” Quality Engineering 24 110-132.

Jensen, W., Anderson-Cook, C.M., Costello, J., Doganaksoy, N., Dorai-Raj, S., Hoerl, R., Janis, S., O’Neill, J., Rodebaugh, W., Snee, R. (2012) “Statistics to Facilitate Innovation: A Panel Discussion” Quality Engineering 24 2-19.

Lu, L., Anderson-Cook, C.M., Robinson, T.J. (2011) “Optimization of Designed Experiments Based on Multiple Criteria Utilizing a Pareto Frontier” Technometrics 53 353-365.

Wilson, A.G., Anderson-Cook, C.M., Huzurbazar, A.V. (2011) “A Case Study for Quantifying System Reliability and Uncertainty” Reliability Engineering & System Safety 1076-1084.

Anderson-Cook, C.M., Crowder, S., Huzurbazar, A.V., Lorio, J., Ringland, J., Wilson, A.G. (2011) “Quantifying Reliability Uncertainty from Catastrophic and Margin Defects: A Proof of Concept” Reliability Engineering & System Safety 1063-1075.

Izraelevitz, A., Anderson-Cook, C.M., Hamada, M.S. (2011) “Illustrating the Use of Statistical Experimental Design and Analysis for Multiresponse Prediction and Optimization” Quality Engineering 23 265-277.

Collins, D.H., Anderson-Cook, C.M., Huzurbazar, A.V. (2011) "System Health Assessment" Quality Engineering 23 142-151.

Lu, L., Anderson-Cook, C.M. (2011) “Using Age and Usage for Prediction of Reliability of an Arbitrary System from a Finite Population” Quality and Reliability Engineering International 27 179-190.

Graves, T.L., Anderson-Cook, C.M., Hamada, M.S. (2010) “Reliability Models for Almost-Series and Almost-Parallel Systems” Technometrics 52 160-171.

Monroe, E.M., Pan, R., Anderson-Cook, C.M., Montgomery, D.C., Borror, C.M. (2010) “Sensitivity Analysis of Optimal Designs for Accelerated Life Testing” Journal of Quality Technology 42 121-135.

Anderson-Cook, C.M., Borror, C.M., Jones, B. (2009) “Graphical Tools for Assessing the Sensitivity of Response Surface Designs to Model Misspecification” Technometrics 51 75-87.

Robinson, T.J., Anderson-Cook, C.M., Hamada, M. (2009) “Bayesian Analysis of Split-Plot Experiments with Non-Normal Responses for Evaluating Non-Standard Performance Criteria” Technometrics 51 56-65.

Anderson-Cook, C.M., Borror, C.M., Montgomery, D.C. (2009) “Response Surface Design Evaluation and Comparison” (with discussion and rejoinder) Journal of Statistical Planning and Inference 139 629-641, 671-674.

Zahran, A., Anderson-Cook, C.M. and Myers, R.H. (2003) “Fraction of Design Space to Assess the Prediction Capability of Response Surface Designs”. Journal of Quality Technology 35 377-386.